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MetabolicKrasinger and colleagues suggest that it may be reasonable to add allopurinol to the pancreatic enzyme treatment regimen in CF patients that have a urine pH of less than 6 and also excrete large amounts of uric acid. Keep Allopurinol out of the reach of children and away from pets. A macrophage migration-inhibition test was negative in the presence of both quinidine and allopurinol. Do not use this medication if you are allergic to didanosine, or if you are also taking allopurinol (Zyloprim) or ribavirin (Rebetol, Ribasphere, Copegus Virazole). In one study in mice, large amounts of allopurinol caused birth defects and other unwanted effects.

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